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Laboratory of Stem Cell and Regeneration
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Publications

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Mo Li and Juan C. Izpisua Belmonte.​ "Organoids — Preclinical Models of Human Disease"​ N Engl J Med 2019; 380:569-579
Year: 2019
  • Organoid
  • Stem cells
Li, Mo, and Juan Carlos Izpisua Belmonte. "Deconstructing the pluripotency gene regulatory network." Nature cell biology20, no. 4 (2018): 382.​
Year: 2018
  • Pluripotency
  • Gene regulatory network
Li, Yu, Renmin Han, Chongwei Bi, Mo Li, Sheng Wang, and Xin Gao. "DeepSimulator: a deep simulator for Nanopore sequencing." Bioinformatics 1 (2018): 10.
Year: 2018
  • Nanopore
  • DeepSimulator
Li, Mo, Zhibo Ma, Sharmila Roy, Sapna K. Patel, Derrick C. Lane, Carly R. Duffy, and Haini N. Cai. "Selective interactions between diverse STEs organize the ANT-C Hox cluster." Scientific reports 8, no. 1 (2018): 15158.
Year: 2018
  • SF1 Tether Elements
  • Selective interactions
  • ANT-C Hox cluster
Mo Li and​ Juan Carlos Izpisua Belmonte. "Ground rules of the pluripotency gene regulatory network"  Nature Reviews Genetics volume 18, (2017): 180–191
Year: 2017
  • Pluripotency
  • Reprogramming
  • Gene
Mo Li, Emiliana Borrelli, Pierre J Magistretti, Juan Carlos Izpisua Belmonte, Paolo Sassone-Corsi & Valerio Orlando. "Gathering by the Red Sea highlights links between environment and epigenetics​" Nature Structural & Molecular Biology volume 24, (2017)​: 491–493 ​​
Year: 2017
  • Regeneration
  • Reprogramming
Yuta Takahashi, Jun Wu, Keiichiro Suzuki, Paloma Martinez-Redondo, Mo Li, Hsin-Kai Liao1, Min-Zu Wu, Reyna Hernández-Benítez, Tomoaki Hishida, Maxim Nikolaievich Shokhirev, Concepcion Rodriguez Esteban, Ignacio Sancho-Martinez and Juan Carlos Izpisua Belmonte.​ "Integration of CpG-free DNA induces de novo methylation of CpG islands in pluripotent stem cells"   Science  Vol. 356, Issue 6337​ 05 (2017): 503-508​
Year: 2017
  • Genomic
  • Human
Shahad K. Alsaiari, Sachin Patil, Mram Alyami, Kholod O. Alamoudi, Fajr A. Aleisa, Jasmeen S. Merzaban, Mo Li, and Niveen M. Khashab. "Endosomal Escape and Delivery of CRISPR/Cas9 Genome Editing Machinery Enabled by Nanoscale Zeolitic Imidazolate Framework." Journal of the American Chemical Society 140.1 (2017): 143-146.​
Year: 2017
  • CRISPR/Cas9
  • Genome editing
  • Endosomal Escape
Keiichiro Suzuki, Yuji Tsunekawa, Reyna Hernandez-Benitez, Jun Wu, Jie Zhu, Euiseok J. Kim, Fumiyuki Hatanaka, Mako Yamamoto, Toshikazu Araoka, Zhe Li, Masakazu Kurita, Tomoaki Hishida, Mo Li, Emi Aizawa, Shicheng Guo, Song Chen, April Goebl, Rupa Devi Soligalla, Jing Qu, Tingshuai Jiang, Xin Fu, Maryam Jafari, Concepcion Rodriguez Esteban, W. Travis Berggren, Jeronimo Lajara, Estrella Nuñez-Delicado, Pedro Guillen, Josep M. Campistol, Fumio Matsuzaki, Guang-Hui Liu, Pierre Magistretti, Kun Zhang, Edward M. Callaway, Kang Zhang and Juan Carlos Izpisua Belmonte. "In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration​" Nature volume 540, (2016): ​​​144–149 ​​​
Year: 2016
  • Genome
  • CRISPR
  • Cas9
Alejandro Ocampo, Pradeep Reddy, Paloma Martinez-Redondo, Aida Platero-Luengo, Fumiyuki Hatanaka, Tomoaki Hishida, Mo Li, David Lam, Masakazu Kurita, Ergin Beyret, Toshikazu Araoka, Eric Vazquez-Ferrer, David Donoso, Jose Luis Roman, Jinna Xu, Concepcion Rodriguez Esteban, Gabriel Nuñez, Estrella Nuñez Delicado, Josep M. Campistol, Isabel Guillen, Pedro Guillen, Juan Carlos Izpisua Belmonte​​. "In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming" Cell Stem Cell VOLUME 167, ISSUE 7, E12 (2016​): 1719-1733​​​
Year: 2016
  • Aging
  • Epigeneti
  • Reprogramming
Mo Li, Juan Carlos Izpisua Belmonte. "​​Looking to the future following 10 years of induced pluripotent stem cell technologies" Nature Protocols volume 11, (2016)​: 1579–1585 ​
Year: 2016
  • Development
  • Stem cell
  • Regenerative
Zhongwei Li, Toshikazu Araoka, Jun Wu, Hsin-Kai Liao, Mo Li, Marta Lazo, Bing Zhou, Yinghui Sui, Min-Zu Wu, Isao Tamura, Yun Xia, Ergin Beyret, Taiji Matsusaka, Ira Pastan, Concepcion Rodriguez Esteban, Isabel Guillen, Pedro Guillen, Josep M.Campistol, Juan CarlosIzpisua Belmonte. "3D culture supports long-term expansion of mouse and human nephrogenic progenitors"  - Cell Stem Cell, (2016): 516-529​ ​ ​
Year: 2016
  • Progenitor cells
Jun Wu, Daiji Okamura, Mo Li, Keiichiro Suzuki, Chongyuan Luo, Li Ma, Yupeng He, Zhongwei Li, Chris Benner, Isao Tamura, Marie N. Krause, Joseph R. Nery, Tingting Du, Zhuzhu Zhang, Tomoaki Hishida, Yuta Takahashi, Emi Aizawa, Na Young Kim, Jeronimo Lajara, Pedro Guillen, Josep M. Campistol, Concepcion Rodriguez Esteban, Pablo J. Ross, Alan Saghatelian, Bing Ren, Joseph R. Ecker & Juan Carlos Izpisua Belmonte. "An alternative pluripotent state confers interspecies chimaeric competency" Nature volume 521, (21 May 2015): 316–321 ​​
Year: 2015
  • Pluripotency
  • Embryonic
  • Stem cell
  • Human
  • Regenerative
Guang-Hui Liu, Keiichiro Suzuki, Mo Li, Jing Qu, Nuria Montserrat, Carolina Tarantino, Ying Gu, Fei Yi, Xiuling Xu, Weiqi Zhang, Sergio Ruiz, Nongluk Plongthongkum, Kun Zhang, Shigeo Masuda, Emmanuel Nivet, Yuji Tsunekawa, Rupa Devi Soligalla, April Goebl, Emi Aizawa, Na Young Kim, Jessica Kim, Ilir Dubova, Ying Li, Ruotong Ren, Chris Benner, Antonio del Sol, Juan Bueren, Juan Pablo Trujillo, Jordi Surralles, Enrico Cappelli, Carlo Dufour, Concepcion Rodriguez Esteban & Juan Carlos Izpisua Belmonte. "Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs"  Nature Communications volume 5, Article number: 4330 (2014)
Year: 2014
  • Anaemia
  • iPSC
  • ESC
Keiichiro Suzuki, Chang Yu, Jing Qu, Mo Li, Xiaotian Yao, Tingting Yuan, April Goebl, Senwei Tang, Ruotong Ren, Emi Aizawa, Fan Zhang, Xiuling Xu, Rupa Devi Soligalla, Feng Chen, Jessica Kim, Na Young Kim, Hsin-Kai Liao, Chris Benner, Concepcion Rodriguez Esteban, Yabin Jin, Guang-Hui Liu, Yingrui Li and Juan Carlos Izpisua Belmonte​. "Targeted Gene Correction Minimally Impacts Whole-Genome Mutational Load in Human-Disease-Specific Induced Pluripotent Stem Cell Clones"  Cell Stem Cell  VOLUME 15, ISSUE 1, (2014): 31-36
Year: 2014
  • Genome editing
  • Cellular
  • Technology
Alessandra Giorgetti, Maria C. N. Marchetto, Mo Li, Diana Yu, Raffaella Fazzina, Yangling Mu, Antonio Adamo, Ida Paramonov, Julio Castaño Cardoso, Montserrat Barragan Monasterio, Cedric Bardy, Riccardo Cassiani-Ingoni, Guang-Hui Liu, Fred H. Gage, and Juan Carlos Izpisua Belmonte. "Cord blood-derived neuronal cells by ectopic expression of Sox2 and c-Myc"   PNAS July 31, 2012 109 (31): 12556-12561
Year: 2012
  • Transcription
  • Cord blood
  • Therapy
Mo Li, Keiichiro Suzuki, Jing Qu, Preeti Saini, Ilir Dubova, Fei Yi, Jungmin Lee, Ignacio Sancho-Martinez, Guang-Hui Liu and Juan Carlos Izpisua Belmonte​​. "Efficient correction of hemoglobinopathy-causing mutations by homologous recombination in integration-free patient iPSCs" Cell Research volume 21, (2011)​: 1740–1744
Year: 2011
  • Mutation
  • iPSC
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